Presented by Vishruta Dumane, PhD, DABR
Associate Professor, Quality Assurance Lead Physicist
Icahn School of Medicine at Mount Sinai
Medical Dosimetry Program Director
Mount Sinai Center for Radiation Sciences at Stony Brook University
Clinical Associate Professor, School of Health Professions, Stony Brook University

This session will discuss the basics of knowledge-based planning, specifically that of the RapidPlan algorithm, how it works, followed by how to build a model, which involves choosing from a set of consistent high quality plans, entering them for training, followed by evaluating the trained model by examining outliers, re-training, re-examining regression and residual plots, constraint tuning, validation and testing.

This session will discuss how to build a simple prostate SBRT model followed by its validation and testing for clinical implementation on standard cases. Application of this same model for treatment planning of prostate SBRT cases with simultaneous integrated boost (SIB) will be discussed so as to treat a greater pool of patients for the same site. We will also discuss the intact prostate, seminal vesicle and pelvic lymph node model, as well as its use for SIB nodal boosts while treating the whole pelvis, followed by the prostate bed and pelvic lymph node model. We will also discuss how the latter can be used for planning anal and rectal sites and the pros and cons of building site-specific anal and rectal models followed by their deployment at various sites in the health system key takeaways and conclusions.

Learner Outcomes:

1. Explain how to build a model
2. Understand and explain when to train optimization structures in RapidPlan
3. Apply a model trained for one PTV dose level for multiple levels such as simultaneous integrated boost (SIB)
4. Understand and explain the process of model transportability to other sites
5. Determine when to build a site specific model
6. Explain the impact on plan quality for a clean model versus one with outliers
7. Explain the difference between plans that have a positive versus a negative impact on plan quality and be able to discern what type of plans to remove from the model

Presenter:
Vishruta Dumane, PhD, DABR, is the Medical Dosimetry Program Director at the Mount Sinai Center for Radiation Sciences Education at Stony Brook University. She is also Quality Assurance Lead Physicist and Associate Professor of Radiation Oncology at Icahn School of Medicine at Mount Sinai, and Clinical Associate Professor at Stony Brook University. She joined the Mount Sinai after completing her training at Memorial Sloan-Kettering Cancer Center in 2005. Her research focuses on the development of treatment planning approaches that are designed to cover the cancerous tumor volumes while maintaining minimum dose to critical organs, developing knowledge-based models for automated treatment planning for various treatment sites including mesothelioma, multiple cranial lesion stereotactic radiosurgery (SRS), gynecologic, prostate, head and neck cancer and cancers of the gastrointestinal tract. She has authored 62 peer-reviewed journal publications, conference proceedings and invited talks. Some of her contributions are key in the use of the deep inspiration breath hold (DIBH) maneuver to reduce low doses to critical organs such as the heart and the lungs while treating breast cancer with radiation, on combining three-dimensional conformal radiotherapy (3DCRT) and volumetric modulated arc therapy (VMAT) to improve regional nodal irradiation and on reducing the dose to organs in the supraclavicular region. She has also authored a book chapter on intensity-modulated radiation therapy (IMRT) for breast cancer and an award-winning article on optimizing treatment positioning to achieve better heart sparing for left-sided breast cancer cases. She is co-investigator on several clinical trials pertaining to the treatment of cancers related to the breast, lung, liver, and gynecologic. Dr. Dumane is a member of The American Association of Physicists in Medicine and The Radiological and Medical Physics Society of New York and is a two-time recipient of the RAMPS Young Investigator Award. In addition to her clinical and research activities, she is passionate about teaching treatment planning and medical dosimetry practices to students. 

Educational Level: Intermediate

ARRT CQR Credit Distribution
There is no credit distribution for this activity